Hi, I started with a walnut small plum size tumor in my kidney pelvis (UTUC) and because my kidney function was diminished I was eligible for Ketruda/Padcev preliminary to an upcoming radical nephroureterectomy. I had 1.5 cycles before it was discontinued because I developed category 3 skin issues which they treated with steroids. After a month on steroids things calmed down. I just had my pre-op CT scan. After first dose the Natera/signatera results were "0" down from 170, and the CT scan just came back perfectly normal. The tumor is gone. I'm astounded. And grateful. Getting ready for the surgery later this month and will hopefully live happily ever after with one kidney.