@mjones149
For Cholestyramine to not affect nutrient absorption it needs to be taken 4-6 hrs from supplements. Since it binds bile acid it can affect absorption of fat soluble Vitamins - Vitamin A, E, D, and K. It gave me muscle cramps in my calf so must have hindered magnesium absorption too. Its binding effect on nutrients makes the timing of taking it problematic. I guess if you need to take it with food you might be able to figure out a time to have a snack and take a supplement 4-6 hrs after dosing with cholestyramine. https://www.goodrx.com/cholestyramine/foods-to-avoid

@mjones149
Forgot to say I was lucky and only had to take cholestyramine at night, around midnight, when I would wake up to pee. Since I was taking it in capsules it was easy to swallow. That one dose was enough to solidify poo's for the following day:)