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Living with Neuropathy - Welcome to the group

Neuropathy | Last Active: Oct 27 5:51pm | Replies (6152)
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@johnbishop

Hi Cathy @catharbert, I take R-ALA 600 mg twice daily along with other related supplements for neuropathy. I think it's always best to talk with your doctor or pharmacist before starting any kind of supplement. I ran mine by my doctor who sent them to a Mayo pharmacist and was told there shouldn't be a problem with me taking them. The pharmacist did say he thought the Omega 3/6 supplement I was taking was a little high but it should be OK.

Here are some links with ALA research you might find helpful.

Critical appraisal of the use of alpha lipoic acid (thioctic acid) in the treatment of symptomatic diabetic polyneuropathy
-- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176171/
Linus Pauling Institute » Micronutrient Information Center - Lipoic Acid: https://lpi.oregonstate.edu/mic/dietary-factors/lipoic-acid
Linus Pauling Institute » Healthy Aging Program - Aging, Stress Response, and Mitochondrial Decay:
-- https://lpi.oregonstate.edu/research/hap/aging-stress-response-and-mitochondrial-decay

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Replies to "Hi Cathy @catharbert, I take R-ALA 600 mg twice daily along with other related supplements for..."
sunnyflower | @sunnyflower | Sep 10, 2020

Hi Cathy, welcome to the group! I am certain that you will find caring, wonderful support and great information here on the blog as I myself have.

My neurologist recently prescribed ALA for me to and I am taking 600 mg once a day. I do not feel my pain is any better. My neurologist said I could increase it and have been thinking about doing that.

Recently there has been discussion about which type of ALA to use and I sent this link someone posted from Oregon State Linus Pauling Institute Micronutrient Information Center about which type of ALA is best: https://lpi.oregonstate.edu/mic/dietary-factors/lipoic-acid

Here is her response: "Most of the research that was done on alpha lipoic acid that showed benefit was done on the S-ALA/R-ALA mixtures. I did try to look to see if there were any studies comparing taking R-ALA only to S-ALA/R-ALA mixtures, but I could not find any."

So I had just ordered the R-ALA from Amazon and will use that but switch to the S-ALA/R-ALA mixture next.

I 'm just wondering how much more to increase it to be safe but yet accomplish less pain. Probably 600 mg twice daily. Of course since I am on so many medications and so many supplements, I will run it by my pharmacist like I do with every new thing I add to my regime because I have learned over time that some of my supplements do in fact have the potential to lessen or increase the effect of some of my prescriptions.

How long did it take 2 work for you? And, in your understanding, is this something you will have to increase in dosage overtime?

I wish you all the best and especially zero pain!

Warmest regards, Sunny flower. 😊

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