@notaquita I've been dealing with NMIBC with CIS (now aggressive pT1) since 2023, and the rheumatic arthritis in my hands has worsened quite a bit: I can no longer remove the cap from a bottle of water. One, six-treatment round of BCG, nine months of Adstiladrin and now a second six-treatment round of BCG in progress. My rheumatologist wants to perscribe Leflunomide (Arava), but can't due to the contraindication with BCG - similar to your issue with prednisone. The rheumatologist and I have decided that cancer treatment takes precedence over treating arthritic pain, but some days I wonder. If anyone knows anything concerning this issue, I'd be grateful for the information.