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← Return to PSMA scan report is in : (((
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That’s great that the PET scan detected his prostate cancer.
It’s not that PSMA PET scans don’t work at low PSAs. What is known is that at low PSAs, the detection rate of PSMA PET is low (see attached chart). His was fortunate to fall in that <33%.
Was his F18 scan the Pylarify
(F18-Piflufolastat) PET scan or the newer Posluma (F18-Flotufolastat) PET scan?
Also, remember that not everything that “lights up” in a PSMA PET scan is prostate cancer.
As it turns out, PSMA (prostate specific membrane antigen) is not really “prostate specific.” There are other organs, tissues, and fluids that naturally express PSMA (without being cancerous) and will show up as physiologic tracer uptake on a PSMA PET scan - particularly in the lacrimal (tear) and parotid (salivary) glands, blood, liver, spleen, pancreas, ganglia, and more, as well as the kidneys, ureters and bladder (as the body tries to quickly excrete the radioligand that was injected).
So, be cautious about excising or radiating everything that shows uptake.
Replies to "That’s great that the PET scan detected his prostate cancer. It’s not that PSMA PET scans..."
@brianjarvis
Do pelvic lymph nodes ever take up that radioligand? I mentioned in a previous post that when my husband's PSA was 8 and the did the PSMA PET scan, two iliac lymph nodes had SUV's of 5.7 and 2.6. They were removed and pathologist found no cancer in the lymph odes.
He had the F-18 Posluma scan.
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@brianjarvis
Thanks Brian for your input 👍.
I appreciate it a lot. I know that you are very studious and did a TON of research yourself, even from the time of your AS. I am really hoping that one node in his groin is not truly a cancer and I was thinking that biopsy of that node would be useful (???) for RT planing and for staging - what do you think about that first step ?