Hello @otisco, Welcome to Connect. I think the answer to your question could be a little different for each of us. I have idiopathic small fiber peripheral neuropathy and like others I take a lot of the same supplements others do. There is another discussion where members have shared their neuropathy journey and what has helped them -- Member Neuropathy Journey Stories: What's Yours?: https://connect.mayoclinic.org/discussion/member-neuoropathy-journey-stories-whats-yours/

Here is an article that lists supplements and vitamins for neuropathy -- Which supplements can help with neuropathy?: https://www.medicalnewstoday.com/articles/326917

Are you able to share a little more about your symptoms and any current treatment you are on?

After bloodwork I was told 2000 mcg. The next bloodwork indicated my level was too high so I needed to reduce it to 1000 mcg. a day. **METHYLCOBALAMIN is the recommended form and My doctor also recommended the sub lingual form. I get the brand Solgar from Amazon. Apparently as we age we need to supplement B12. Unfortunately this did not seem to affect my peripheral neuropathy symptoms, but I still take it

@otisco I have Small Fiber Peripheral Polyneuropathy as a result from B12 deficiency which slowly developed through my forties. Now that I've been regulated through injections, I take oral B12 2,000 mcg per day and a daily B Complex with 30 mcg B6. Too much B6 creates PN, too little B12 creates PN, it's a balancing act, one that your Dr. should be aware of and advise on. Dangerous area. Good luck.