@runningy Have had my third infusion. Most noticeable side effect is fatigue, especially in my legs after only moderate exercise (6000 steps, nine holes of golf w/cart). Pain making it difficult to walk, moderated after 24 hours, gone in 48 hours. Is this to be expected as I continue with treatments? The other issue was itchy skin, but a biopsy suggests it is a autoimmune reaction that started before the Libtayo infusions and is probably unrelated to SCC. It has subsided greatly!