@md79 I was lucky that my endocrinologist agreed to put me on hrt. I was 14 years post menopause. One thing the hrt did help me with was my lipoprotein a which was slightly out of range. The estrogen has helped lower it considerably. I'm hoping to just stay on it forever and use it as my only follow up to Tymlos only using Reclast if absolutely needed. We'll see. It's so difficult to know what to do! Best wishes