Connect
← Return to Salvage Radiation Therapy with or without ADT added?
Discussion
Salvage Radiation Therapy with or without ADT added?
Prostate Cancer | Last Active: May 29 7:37pm | Replies (49)Comment receiving replies
@bikeman1
These are pretty standard recommendations when reoccurrence happens. 3 1/2 years after my prostatectomy, my PSA started rising, and I had 40 sessions of IMRT. They didn’t have IGRT 12 years ago or I would asked for that.
You also want the pelvic lymph nodes radiated. Pretty standard procedure.
Hopefully this will get your PSA down to undetectable for a while, and you won’t need ADT. Of course your doctor will Probably want you on it because of the aggressiveness of your diagnosis. See if you can use Darolutamide, One of the other glutamine instead. Enzalutamide Has been approved for use without ADT.
Another option might be estradiol patches, Which work as well as ADT but worked totally differently on the body. Not sure if your doctor is really up on them, Many will not approve.
Replies to "@bikeman1 These are pretty standard recommendations when reoccurrence happens. 3 1/2 years after my prostatectomy, my..."
Connect
@jeffmarc
Thanks as always for your insights. The RO recommended Orgovyx because I am in the Luminal B subcategory. The NRG GU006 (BALANCE) study showed better outcomes for this type of aggressive cancer with ADT added.
I am worried if the PET confirms the 2 lymph nodes are involved they will want me on an ADT AND an ARPI (like the ones you suggested). I never thought of looking at an ARPI INSTEAD OF ADT.
And I have asked about the patch, which I will discuss with my MO on 6/16 along with these other drug options.