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Treatment of lung adenocarcinoma
Lung Cancer | Last Active: Jun 22 9:07pm | Replies (38)Comment receiving replies
@lls8000 Two+ weeks ago I started the TEPMETKO tablets (450 mg total/day)... a usual targeted therapy for the MET exon 14 NSCLC.
Decided against doing the clinical trial. So far, no noticeable side effects but my most recent labs (after 14 days of Rx) showed significant kidney function decline and a lower score for Lipase. Is this usual? I'll be talking to my oncologist in about 5 days.
Replies to "@lls8000 Two+ weeks ago I started the TEPMETKO tablets (450 mg total/day)... a usual targeted therapy..."
@mangolinda8191, Please let us know what your doctor says about the kidney numbers. It's good that they are watching you closely with lab work. I'm wondering if it's a spike that might occur at the initial treatment, but may resolve as your body adjusts or if it's expected to continue. These targeted therapies can be powerful and effective, but they can come with a wide range of side effects too. I am not a clinician, but I take a different targeted therapy. With mine, it's not uncommon to reduce the initial dose, so that may something that you can ask about too. Are you feeling any worse or better after starting the TEPMETKO?
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@mangolinda8191 I'm glad you're seeing your oncologist soon and that you aren't having noticeable side effects. It looks like kidney function is frequently affected by Tepmetko. Let us know what you and your doctor decide is best.