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magicbearcat1 avatar

PET Scan or not yet?

Prostate Cancer | Last Active: 1 hour ago | Replies (26)

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Profile picture for Jeff Marchi @jeffmarc

@wheel1
As you say, this is being looked into, but there are some definitive studies. I saw another study which talked about the fact that people with advanced prostate cancer cases had much lower overall survival if they didn’t get salvage radiation.

Investigators identified an increased risk of mortality among patients with at most 1 high-risk factor who initiated salvage radiotherapy with a PSA level of over 0.25 ng/mL vs patients whose level was 0.25 ng/mL or less (adjusted hazard ratio [aHR], 1.49; 95% CI, 1.11-2.00; P = .008).
https://www.cancernetwork.com/view/psa-cut-point-indicates-when-to-start-salvage-radiotherapy-in-prostate-cancer

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Replies to "@wheel1 As you say, this is being looked into, but there are some definitive studies. I..."

@jeffmarc

I know Jeff, I do not know if people are actually reading studies ?

This subject is not about "opinions" or "anxiety", it is about multiple studies done over the years that continually proved one and the same thing over and over again - salvage before uPSA reaches 0.25 gives significantly better results, it is not even a question.

ADT - most people here had either short or long term ADT and most are doing just fine, some had zero SA during short term ADT and besides, what has to be done has to be done.

By the same token one can argue that no treatment should be done at all in any stage since treatments effect "quality of life" ?

If one has indolent cancer and a luxury of "observing" it over the years inching from 0.10 to 0.11 in a year , than of course - go for it !