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What's Next After SBRT and ADT?

Prostate Cancer | Last Active: 5 hours ago | Replies (16)

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Profile picture for jim18 @jim18

The problem with recurrence is most is out of our control. The two largest factors are genetics (Decipher test mentioned can give you some insight on your situation) and how through your treatment was (positive margins on surgery, misses on radiation, or undetected micro-metastasis that PSMA PET could not detect). Read the Active Surveillance - Systematic Review post for information on lifestyle actions (the poster also has a website that covers many supplements, etc.). Exercise and diet seem to have the most impact and you have those covered. From a medical standpoint more ADT will reduce if not eliminate prostate cancer recurrence, but studies have shown that the increase in all causes of death from the ADT side effects out weights any population benefit from decreased prostate cancer death. Unfortunately, there are more snake oil cures or preventions for cancer than just about any other disease. People like to be in control, even if it is an illusion. If one of these cures gives you a sense of comfort and control than go for it. Just keep the PSA testing current with everything else you do.

For your current situation your PSA is still being suppressed by ADT and may be until early August. It is not unusual for PSA to become detectable again once testosterone returns after radiation and ADT. PSA remaining under 0.25 is predictive of a low recurrence rate while > .50 has significantly more recurrences.

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@jim18

I especially liked your comment that "studies have shown that the increase in all causes of death from the ADT side effects out weights any population benefit from decreased prostate cancer death." Doctors seem to want these studies to remain a secret because ADT shots are about all they have to offer you once surgery or radiation are finished. My doctor even suggested Trimix even though I have zero libido which would prevent it from working adequately.