@tigreyes2004

Finding a medication or combination of meds can take a very long time. All of the meds labeled for neuropathy either did nothing or I had unacceptable side effects, the worst one being Lyrica. It put me in the hospital for a few days. The bummer - it was actually helping with the pain.

I finally had a spinal cord stimulator implant in June, 2017, and it was wonderful!!! I had 80% pain relief. After a year, I started needing to have the stimulator settings tweeked every 3 months. I had been seeing a pain specialist, who took the next step in finding a medication that I could tolerate, and I tried a bunch of off label meds. I was taking morphine sulfate contin before the scs implant, and was able to reduce the dosage, but I still take it because it takes the edge off the pain.

A couple of months ago the pain specialist started me on imipramine, and as I increased the dosage it increased my pain relief. Normally I would have had the Abbott rep adjust my stimulator, but I'm not doing anything until my next appointment with the pain specialist, and evaluate the efficacy of Imipramine. My feet hurt, but it's bearable. I keep my fingers crossed.

So, I would say, don't be surprised if it takes a while to land on the medication that gives you relief without unacceptable side effects. It generally means taking a medication for six weeks to assess its benefit or side effects. My siblings all have taken Gabapentin with good results, but it didn't help me.

Jim