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Living with Neuropathy - Welcome to the group

Neuropathy | Last Active: Oct 27 5:51pm | Replies (6152)

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@rosy33

I believe it is more about B6 rather than B12 which can exacerbate neuropathy if you have too much of it. My blood levels on B6 are normal so I decided to take a multi with 12.5 of B6 in it. After a week my feet and legs are bright red and hot to the touch. I developed a red rash around my right ankle and I have pain all day. I usually have most of the burning pain at night and am able to function during the day, but not since I've been on the B6. I stopped taking it today so I will post here in about a week to see if it helps. The doctors tell you that the B vitamins in combination will work, but I wonder how many of them take the time to research the adverse reactions of B6 and neuropathy.

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I stopped taking B12 which seemed to make my SFN worse and then stopped the low dose B Complex, my neuro said if my levels were within range , no need. I do think the RAla, magnesium, biotin and omega 3’s have helped.

@rosy33 you are so right about B6. Here are some of the sites I've used in the past when researching B vitamins.

VITAMIN B6 TOXICITY
http://www.easy-immune-health.com/vitamin-b6-toxicity.html
B Vitamins for Neuropathy and Neuropathic Pain
https://www.omicsonline.org/open-access/b-vitamins-for-neuropathy-and-neuropathic-pain-2376-1318-1000161.php?aid=90896
B6 section it explains -- too much or too little gives neuropathy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/
FDA Safety Alert: Biotin Can Affect Medical Test Results
http://cle.clinic/2G6Mp4y
NIH - Nutritional Neuropathies
-- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199287/

Vitamin B6 Toxicity Revisited: A Case of Reversible Pyridoxine-associated Neuropathy and Disequilibrium. (P4.021)
-- http://n.neurology.org/content/90/15_Supplement/P4.021