@gravity3 Never took anabolic. Did not know what they were. When I went for second opinions with the various folks who treat osteo only one mentioned anabolic and that is what she would have started me on (a rheumatologist). My endocrinologist started me on Fosamax, did not know enough at the time to even have a discussion about what else is out there or why Fosamax, other than it is a first line treatment (although apparently if severe enough anabolics are a better start?) He did say he did not like Prolia. Dexa in April of 2024 was spine -2.9, left hip -2.8, left femur neck -3.5; after Fosamax treatment April 2025 spine -2.6, left hip -2.6, left femur neck -3.5. Reclast infusion in July 2025; no dexa until 2027 so other than CTX (which doc said indicates Reclast is working) which was was 52 in April of 2025, 78 in April of 2026 and NTX (normal range) there is no further testing until April of 2027. It will be time for another Reclast infusion and am once again extremely anxious about that without a dexa scan, as I have discovered through this site that meds work sometimes, sometimes not so much! My doctor said that Reclast should work well; and it was possible I would only need one infusion but at my most recent appointment he indicated it would be highly unlikely that it would have worked well enough to skip a second or more infusion.