I'm not a medical doctor, just a patient (high grade, non-muscle invasive). But, here is my understanding from a brief search. BCG is the go-to treatment for non-muscle invasive bladder cancer and, based on a Slone Kettering study I just read, successful responsiveness to BCG, is a prerequisite before going to Dem Dose which is then used along with BCG in further treatment. If you are responding well th BCG, my impression is they won't add in Dem Dose yet. Dem Dose is an abbreviation of a chemical compound introduced into the bladder just like BCG. I should add that I have only been treated with BCG so far. 7 years ago it was found and BCG seemed to work and held for 5 years. But, because of scarcity, the recommended follow-up didn't take place and the cancer returned. I'm with a teaching hospital now that never ran out of BCG. I'm back to a regular schedule that, God willing, will continue it's success.
If there is a urologist/oncologist out there who can enlighten us further on Dem Dose, please do.