@tigreyes2004, @rwinney It appears that both of you have been trying to find the best medication for pain, depression, and anxiety and especially as those quests apply to Gabapentin vs Cymbalta.

Since most of us have to deal with all three symptoms, it is interesting to see what works and what doesn't, what side-effects have interfered with the purpose of the medication, and what is the best time of day to take these medications?

Sometimes when changes are made, we wait somewhat anxiously for positive results whether that be the disappearance of side effects or the appearance of pain amelioration. And when they work, we want the positive results to make a difference and last a long time.

Just for the record, after some restless and inconclusive experimenting, I am pretty settled on Cymbalta (duloxetine) 60 mg in the morning and gabapentin,1200 mg before bedtime. We are all so very unique and are bodies seem to march to their own drummer. Can you imagine what our medical providers must filter through for each and every patient? Thanks for posting your information today and please let us know of improvements in pain control or decreases in anxiety and depression which should actually translate to pain reduction.

Have a lovely, breezy afternoon. Chris

Thank you. Norco gives me nausea all pain pills do & plus the constipation. I sure hope this Cymbalta doesn't. The Lyrica doesn't give you any side effects?