← Return to Hormone Therapy (ADT) when ArteraAI Test says it's not necessary

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Profile picture for Jeff Marchi @jeffmarc

@heavyphil
He said essentially that the cancer cells will accumulate and get hit by cosmic rays and then convert to resistance.

It makes me think that when you are on ADT some cells still accumulate but if you are on estradiol, you don’t have that problem. I don’t know if that is true, I do know the few people that I know of that are on estradiol do not have a problem yet. And some people that were on ADT for many years alone, didn’t have that problem.

I do know that I was on only ADT for 2 1/2 years and became castrate resistant. Something happened to those cells. Predictions of how soon somebody will become castrate resistant after being on ADT alone say, it’s a median of two years.

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Replies to "@heavyphil He said essentially that the cancer cells will accumulate and get hit by cosmic rays..."

@jeffmarc OK, that’s interesting…but I think in your case the BRCA mutation pretty much makes your cancer aggressive which then leads to castrate resistance; I’ve read some studies - I’m sure you have read them all - where men are first tested for BRCA only because ADT stopped working; once they were found to have the mutation they were placed on PARP inhibitors.
Are you on one?
I think you were on Zytiga or Nubeqa but those aren’t PARP inhibitors. Thanks!
Phil