← Return to Bone turnover markers (CTX and P1NP): do you have a baseline?

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@mayblin - did you take any other bone drug after Tymlos or just depend on HRT to maintain the gains? I have started HRT 3 months prior to the end of my Evenity treatment. What optimal hormone ranges are you looking for?

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Replies to "@mayblin - did you take any other bone drug after Tymlos or just depend on HRT..."

@singingbones i used Forteo then transitioned to HRT with no other osteoporosis meds, so estrogen serves as an antiresorptive during my maintenance phase.

Since CTX (resorption) tends to have a small rebound toward or above baseline within 1–3 months of stopping Evenity, and the fact that it takes a few months for estrogen to reach max effect, having 3-4mos of HRT already in place like you have is a huge plus in my view.

Have you checked your CTX labs? I think it’s a great way to verify HRT's effect. My doctors don't focus on serum estradiol levels, but they check my CTX periodically and order annual DXA scans.

Hope this info helps somewhat. Best of luck and please keep us posted.