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Replies to "@pat9892 I’m not sure I understand the comment about re-running the numbers. My understanding is the..."
Breast Cancer | Last Active: May 17 9:15am | Replies (15)
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@pat9892 I’m not sure I understand the comment about re-running the numbers. My understanding is the ER, PR and HER2 numbers are run on the tumor to determine its makeup. Same with the Ki67 and oncotype. Doing treatments wouldn’t change any of these? If they were rechecked, it would be done off the same tumor tissue that was saved, not a blood test. Are there other numbers that should be rechecked? My oncologist uses the Cea and tha Ca27-29 tumor markers and rechecks these regularly. There are some who don’t recommend them because they aren’t totally accurate (and it has caused some problems with my treatment) but they are blood markers, not actually tumor tissue markers.
Replies to "@pat9892 I’m not sure I understand the comment about re-running the numbers. My understanding is the..."
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@mistymar
My initial numbers were from a fine needle biopsy (A very small sample of tumor tissue). Once the tumor was taken out and tested , a couple of the numbers were significantly different, My PR %went from 42 to 0 , my KI 67 went from 21-30 to 6-10 . This changed my diagnosis from luminal A to Luminal B. Also , as soon as I found out the fine needle biopsy came back as ER + , I immediately stopped my estrogen replacement therapy which was probably responsible for lowering my KI 67 score … since it was 21 days before the mass was removed