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Barrett's esophagus: What to expect?

Esophageal Cancer | Last Active: 6 hours ago | Replies (17)

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@jeahunt12 I was diagnosed with Barretts in 2015, a results of chronic acid reflux over many years. I was having trouble swallowing, I had the endoscopy and dilation of the area in my esophagus where the metaplasia had occurred. I was then put on a 3-year endoscopy schedule (2018 and 2021, 2024), and 40mg Omeprazole. Biopsies were taken at each of these procedures.
The biopsy analysis in 2024 showed a likelihood of dysplasia (pre-cancerous), so I was placed on a 6-month endoscopy schedule. A new GI doctor came into the practice in late 2025, he did my late 2025 endoscopy and sent the biopsy samples to both the regular testing lab, and also to a “Tissue Cypher” test that tests the likelihood of dysplasia advancement. That result came back as “very likely” to become cancerous.
Consequently I had a “Radio Frequency Ablation” (RFA) in February of this year, where the Barrett’s cells were burned off and new “normal” cells replaced them. Disclosure- This procedure has an extremely painful recovery, it’s like being very badly sun-burned on the inside of your esophagus, and I also had trouble swallowing from the swelling, however now (3 months later) I have no pain and everything appears to be normal. I go back in for an endoscopy on May 27, where any remaining Barretts cells will be ablated, and just to check on how things are down there. I am also now on 80mg daily of Omeprazole.
I hope this helps you with your question, please feel fre to DM or reply back here with questions.

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Replies to "@jeahunt12 I was diagnosed with Barretts in 2015, a results of chronic acid reflux over many..."

@brucekn

Hi, how are you doing? I just came across this if you don’t mind. I got diagnosed with BE in Dec 2025. I asked for an EGD when I had my first colonoscopy due to my dad dying from esophageal cancer when I was 11 years old. I’m 54 now. (My dad caught it too late, btw, it had already advanced.) I’m glad I asked for the EGD and caught it early even though I’ve been on meds for years. (It’s 1cm, short stage. No dysplasia for now.) I just had hiatal hernia repair surgery and a Linx device installed two weeks ago bc my issue is not only genetics related but anatomical. My question is, should I request a “tissue cypher” test and did they charge you? I’ve had 3 egd’s since December so I’ve got samples. I’ve heard insurance may or may not cover it and it’s around $5k. The company that issues the test, Castle Biosciences, said if insurance won’t pay for it, they won’t charge me. I think it’s worth it if the surgeon doesn’t see it as urgent. I want the BE removed before it advances considering my genetics. Ugh. Were you billed for the test or did insurance cover it? Thanks for your response. -t