I had stage 4 lung cancer but after 2 years on Tagrisso my Pet scan cannot detect any cancer. I have had lots of side effects but have conquered most of them. For muscle cramps or spasms, spray Magnesium oil directly on the area. The cramp should release within a few seconds. I had Diarrhea for months until I found a product that worked. It is called EMMA , made by Enclove Bioactives. I take it every day and no more diarrhea. Make sure that you order it directly from the company (I found it on EBAY, but it is a fake product). For mouth sores, I tried the magic mouthwash and it just made my mouth numb, no healing at all. Rinse with baking soda water several times a day. Also, check your toothpaste. I read that fluoride can aggravate mouth sores, so I started using Dessert Essence toothpaste with tea tree and neem (no Fluoride). Within a few days, all of my mouth sores were gone and have not come back. I also had a stomach issues. I found that acupuncture really helped. Hope this helps you.