← Return to Vitamin K: High Doses of MK-4 and MK-7 Show Promising Results

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@jozer
I take: 180mcg Menaquinone-7 (MK7) - TrueVantage brand and
45,000 mcg (45 mg) of vitamin K2 (menaquinone-4) - Life Extension K2 High Potency brand

I don't think doctors have much interest in vitamins and supplements, other than calcium and Vitamin D. Japan has done studies that found Vit K is beneficial.

Here's a study published by the National Library of Medicine in 2022 that says:
"6. Conclusions
VK supplements showed a small impact on the BMD in postmenopausal or osteoporotic females. A clinically significant effect was seen on clinical and vertebral fractures. The additive effect of VK was found more efficacious. It is positively effective when used in combination or with concomitant therapy. However, the VK2 form displayed a major role in bone formation and was found more effective than its other forms. The meta-analysis of the studies concluded that VK helps to decrease the overall fracture risk, but little evidence showed an insignificant effect on BMD. Long-term use of VK with high dose intake proved to have a beneficial role in increasing BMD and helping to reduce fracture risk in adults. Therefore, more studies are required to strengthen the support of VK as an anti-osteoporotic treatment.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9138595/

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Replies to "@jozer I take: 180mcg Menaquinone-7 (MK7) - TrueVantage brand and 45,000 mcg (45 mg) of vitamin..."

@daisy17 What is interesting to me is that bisphosphonates are found to increase BMD but studies shows they offer minimal fracture prevention benefits.

On the other hand, this study says that Vit K may not increase BMD but offers benefits in preventing fractures.

BMD is important, but more important is fracture prevention.