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Mounjaro (tirzepatide) in regards to anti-inflammatory-power
Polymyalgia Rheumatica (PMR) | Last Active: May 11 9:01pm | Replies (7)Comment receiving replies
Good article but I would be cautious. The use of GLP-1 in anti-inflammation treatment of autoimmune diseases is, by the article's account, still in trial. Getting a Dr to prescribe for PMR might be hard to find, as well. Looks promising, however. If you have a weight problem that warrants a GLP-1 then maybe you could get a two-for or additional benefit.(?).
I would suggest trying Kevzara for PMR in order to help taper and get off the prednisone ASAP. Being at 9 mg, you probably did not start long ago (3-4 months). My pred taper was 9 months and I had a prescription for Kevzara but never filled it due to doing well (no flares) with my pred taper. You have options.
Replies to "Good article but I would be cautious. The use of GLP-1 in anti-inflammation treatment of autoimmune..."
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@petermccarville
I'm in my final stages of tapering, at 1.5 mg. Started at 60mg last October. I found right abound 3mg that little 'signs' (or my hyper-sensitivity due to fear) were flaring. Not PMR tho, like lower leg pain, feet numbness....weird stuff. That's when I slowed down to a .5 decrease every 3 weeks. This slower pace seems to have calmed things down. I have not used any other drugs to assist the taper. I will say it is really hard to know if prednisone related or other. I have GCA and no signs of PMR yet. Now that you are off steroids, are you using any maintenance drug? Did you have steroid side affects? I have gained weight and so wish I had my old self back. Maybe GLP1 would give me that? A1C is elevated but Doc tells me its the prednisone. Are you back to your old self PeterMcCarville??