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← Return to GLP-1 Drugs Effects on PMR
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Polymyalgia Rheumatica (PMR) | Last Active: 6 days ago | Replies (41)
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I went on zepbound a couple months after starting Prednisone for my PMR because of the weight gain. What I noticed was that the zepbound increased my fatigue. Not sure if it helped with the aches and stiffness and inflammation because the prednisone was already working. I did end up losing 50 lb which I think in the long run really helped with not carrying around extra weight and the discomfort that comes from that. I can tell you,now that I'm off the prednisone my aches have come back and I am glad I'm not carrying around an extra 50 lb
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@joyl263 The prednisone has been difficult for me even though it controlled the PMR symptoms. Side effects for me have included anxiety, jitteriness, brain fog, emotional fragility, fatigue, sleep disruption, and feeling generally “off.” Because of that, I am cautious about adding or continuing anything that could potentially worsen GI symptoms, dizziness, nausea, fatigue, or overall functioning while I’m tapering.
It is helpful hearing experiences from people who have tolerated GLP medications well long term while also managing PMR. Do you have any advice for someone trying to balance PMR treatment, prednisone tapering, and concerns about starting a GLP medication?