@mwpcaretaker I'm currently taking 100mg Labetalol first thing in the morning and 400mg at night. I have on hand .1mg Clonidine to offset hypertension spikes and 5mg Midodrine to help with hypotension lows. It took a long time to come up with this combination, but research now supports it. They suggest it can't be controlled, rather to treat the symptoms for quality of life. So far it has helped even though I still experience exaggerated highs and lows. It sounds like your husband's condition is a challenge. I hope he finds what works for him.