I have LC/CFS and take 0.9mg/day of Abilify. I think it has helped me tremendously with reducing fatigue, PEM, brain fog, photophobia and other symptoms. But it is hard to know for sure as I am taking Naltrexone at the same time. I think I had more or less settled my Naltrexone dose when I started Abilify. I continue to improve tremendously - about 75% symptom reduction. Both meds are prescribed by the LC/CFS clinic at Stanford.