@roslynroslyn I would sure like to know what they are and how to stop them. My electrolytes are always great. My one toe has been blackish for almost 2 yrs straight now. Saw a podiatrist and he was alarmed at how my feet moved and referred me to Mayo but they denied the referral. Rheumatologist I saw locally completely dismissed me and got upset because so much is going on. It was pretty much a waste of my time. So here I am looking for answers and hoping my experience might help someone in some way. Until then I am going to keep taking the LDN and prednisone until they figure out something