@jeffmarc - Hey Jeff...Can you point me in the right direction to the studies that concluded that treating the prostate in very aggressive cases has no benefit? I have an appointment coming up with my GUO and thoroughly enjoy discussing stuff like this with him. Most times he already knows but sometimes I catch him when he's behind on his reading and surprise him. Those are always fun moments. Last happened during our Pluvicto vs TP53 discussion last year. Love the look on his face when I catch him on something new. Just a bit of a game we play.