← Return to PSA at 6 months after salvage RT—not so good

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PSA at 6 months after salvage RT—not so good

Prostate Cancer | Last Active: May 23 7:45am | Replies (14)

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Profile picture for Jeff Marchi @jeffmarc

As you have found, a high ALP can mean that the cancer has come back in the bones. You need to get a PSMA pet scan to see if anything can be found. They may want to wait until your PSA hits .2 but that may not be necessary. You’ve had prostate cancer and it is at best in remission. This indicator that it could be in the bone Is a lot more significant because of your history.

Watching the PSA test to see if it is rising at a significant rate is really the only thing you can do, Unless your doctor thinks a PSMA pet test would be useful.

At this point, I would want monthly PSA tests. My doctor actually started me on monthly PSA tests when my PSA started rising 2 1/2 years after salvage radiation.

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Replies to "As you have found, a high ALP can mean that the cancer has come back in..."

@jeffmarc Thanks Jeff. Yes, I am going to insist on monthly PSA testing. Need to see for certain which way it is trending, especially in light of the ALP result.

I had elevated ALP about 8 years ago. My PCP at the time was a bit alarmed because it was a potential marker for bone mets. I was referred to an endocrinologist who, with further testing, determined a Vitamin D deficiency. That was corrected, and my ALP has been normal, until this last week. After a routine metabolic panel showed elevated ALP (149), my PCP ordered a Vitamin test and a hepatic panel. ALP came back at 150, all other liver values were normal and Vitamin D was normal. I got the PSA test on the same day. The combined ALP and PSA are concerning to say the least.

I going to message my urologist as well with all the data. He’s a specialist in advanced PCa and seems to have a proactive approach.

Currently, I thinking that I should test PSA in a month, and then if there is an upward trend, a PSMA PET scan would be the next step. But, I am open to sound advice from any quarter. Maybe there is reason to act sooner on the PSMA PET scan.