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Stage 4 Metastatic - what to expect after 6 months

Prostate Cancer | Last Active: 7 hours ago | Replies (29)

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Profile picture for canadaanne @canadaanne

My husband has a similar diagnosis and story.
He was diagnosed in January. PSA over 900, Gleason 8, metastatic…
He is on triple therapy - Orgovyx, Darolutamide, and Docetaxel. 5 of 6 rounds of Docetaxel as of yesterday.
His scans and bloodwork show the treatment is working as it should. He had radiation on a lower spine metastasis in March.

There isn’t talk of radiation on the prostate itself though? Do you know their rationale for that when the cancer is metastatic? We understood that they typically only treat the prostate directly if the cancer is localized?

I wish you well and hope the rest of your treatments are successful!

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Replies to "My husband has a similar diagnosis and story. He was diagnosed in January. PSA over 900,..."

@canadaanne I think research so far has showed a benefit for radiation to the prostate for oligometastatic prostate cancer, but not (yet) for high-volume metastatic prostate cancer.

@canadaanne
Recent studies have found that treating the prostate in very aggressive cases has no benefit. Long-term progression free survival did not change.

Over at ancan.org Weekly online advanced prostate cancer meetings they have been recommending treating the prostate to everybody for years. When this came out about six months ago, they changed their tune and no longer recommend it with serious cases like your husband’s.

Ask your doctor about it. It may make sense, it may not. Has the treatment he has already had eliminated the need for it?