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I am A 70 year-old female, who just had a left nephrectomy in March .Histology G4 negative margins for invasion. I did have a pet scan prior to removal of the kid kidney, which was negative. First visit with oncologist, suggesting immunotherapy. My concern is the side effects. I live with my daughter who has intractable seizures, and a husband who is severely depressed. I am concerned about the side effects and how debilitating they could be. Any thought's , I’m back-and-forth. My window ends in 2 1/2 weeks.

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Replies to "I am A 70 year-old female, who just had a left nephrectomy in March .Histology G4..."

@reef67 not sure what you mean about the window.
I started on keytruda November 7 and had debilitating severe side effects. Went in prednisone tapers and that helped greatly. They didn’t have me continue with Keytruda and changed to Opdivo and Cometrx with very little side effects. Suspiciously it may be that because I’ve been in 5 mg prednisone and 400 mg hydroxychloroquine daily that it greatly lessened the side effects. I am not a Dr. If there is no evidence of the cancer metastasizing via scans, maybe you should wait. I don’t know if immunotherapy is used as a preventative or only if there is evidence of metastasizing. If you start immunotherapy maybe it’s best to start prednisone and/or hydroxychloroquine before.
Everybody responds differently and your Drs know best.
Hope my experience helps

@reef67 my 54 year old son was blessed to have no untoward reactions except a slight itchiness in the beginning and maybe fatigue for the evening after the treatments. I have seen other posts with not so great reactions from others. I suspect it is very individualized. My son is glad he went forward with it. I hope you make your"thoughtful decision and do as well as he did!