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DiscussionLooking for research re: taking AI drugs vs not taking them
Breast Cancer | Last Active: May 15 10:12pm | Replies (170)Comment receiving replies
Replies to "@kcalhoun So glad the weight issue cane up! I do a lots of research as well...."
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@triciaot Hi! I'm sending my positive waves of healing to you from afar! < 3 Just one finer point to put on this. It isn't just that the estrogen "is present in fat." The adipose (fat) tissue is PRODUCING the estrogen, making it the primary source once the ovaries stop. The enzyme in fat is aromatase, which is the thing you're trying to block with AIs. Significantly overweight women therefore have more circulating estrogen in their body, which then can stimulate the growth of hormone+ breast cancers. I'll repeat my warning that for those with a LOT of extra fat in the midst of a breast cancer battle, AIs may be the way to go to stop that process. I went the GLP-1 way because I couldn't tolerate any of the AIs. And that one more significant thing to know - how much is that AI going to reduce your risk specifically. I ain't living a life of misery in exchange for a 1-2% risk reduction. But for other women, the risk reduction is totally worth it. Not sure what yours is? Go back to those Predicts reports with your unique profile in there. You will see it clearly. Prayers for everybody!!! < 3