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Started Repatha - Side Effects

Heart & Blood Health | Last Active: 6 hours ago | Replies (524)

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I have been on Repatha for 6 months. It works to lower LDL- and since I cannot tolerate statins, I was celebrating. However, for a few days after each injection, I experience flu-like symptoms and back pain. I dealt with it until my last shot 3 weeks ago. Flu symptoms turned into a 103 fever, and a UTI turned into a raging kidney infection. Am I right to draw a connection to Repatha? My cardiologist said the only side effects would be soreness at the injection site... right! Would love to hear from other users.

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Replies to "I have been on Repatha for 6 months. It works to lower LDL- and since I..."

Hi, @jopap and welcome to Mayo Clinic Connect. Flu, UTI and key infection sounds horrible. @llynch17056 listed common side effects that you will want to review.

From my own experience I key into your comments about having these symptoms progressively getting worse. I believe side effects snuck up on me. It does take about 3 months to get most of the drug out of your system, so if you discontinue side effects wouldn’t immediately go away. Definitely let your prescribing doctor know if you make changes.

Are you planning to discontinue, or take a break from Repatha?

@jopap I want to also mention that I am terribly statin intolerant and get very sick. Eventually Repatha made me very sick also. My cardiologist was about the same as yours. UGH! I got a new cardiologist that knows side effects and believes me. That was so nice. He suggested Nexletol which is for persons intolerant to statins and Repatha. I’m on week 10 with zero side effects. I well know side effects can show up, but so far this is the only thing that worked for me. Actually I’m feeling great.