← Return to bone pain four months after Reclast Infusion

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bone pain four months after Reclast Infusion

Osteoporosis & Bone Health | Last Active: May 12 12:12pm | Replies (93)

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About 3-4 weeks after my second infusion of Reclast in November 2025, I suddenly developed significant bilateral shoulder pain. Discussed it with my PCP who, after researching, felt it was not related to the infusion because side effects were not usually delayed. However, the pain continues, more intensely at night, making movement in the morning difficult. Less often, I have had pain in my hips, thighs and lower legs. I hydrate well and get no real consistent relief from NSAID’s or Tylenol. It seems unlikely that I developed osteoarthritis in both shoulders at once!
Prior to the second infusion , the Endocrinologist saw some improvement in bone density. I meet the criteria for osteopenia in most of my bones, with osteoporosis in my right forearm only. Wondering if anyone else has experienced this and if it improves by stopping any further infusions?

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Replies to "About 3-4 weeks after my second infusion of Reclast in November 2025, I suddenly developed significant..."

@catkm and yet the drug literature for Reclast states that pain, sometimes severe, can occur months after infusion. I have experienced pain (not debilitating; but sometimes severe, comes and goes) in multiple body parts; fingers, forearm, legs, back, feet, ankles, etc. Also had bone pain on Fosamax (also a bisphosphonate); doctor had me take a two-week break (twice in the almost 1 year I was on Fosamax) because of pain. But he said reclast can't be causing pain months later. I say BS! I am due for another infusion around July, but DEXA is every two years so no testing (other than CTX, NTX, and other bloodwork for infusion) so I will not know completely how or if my bone density has improved.