@jack1724 Oh, I'm so sorry. I have fatigue also, comes and goes. Usually it comes if I have overexerted myself. It's such a delicate balance. My primary has just ordered Low Dose Naltrexone for me. I was on it four or more years ago after I first was diagnosed with LC. It helped with the fatigue. Not a complete fix, but it did help. But it was discontinued because, at the time, it was considered experimental and its efficacy was based on anecdotal evidence. Now there are several published studies (double blind with placebos) showing that it does help around 75% of LC patients to rein in their fatigue. I will begin taking it as soon as it arrives, probably by next Monday.