Hi @friendz4 it's good to ask questions. I'm assuming you told your doctor you are not sure about the plamapherisis treatment. What did he say? I was not familiar with the treatment so did a search. I have no medical training or background but reading about it may help you feel a little more comfortable with it.

Plasma exchange treatment of peripheral neuropathy associated with plasma cell dyscrasia.
-- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1027944/

Plasma Exchange in Neuroimmunological Disorders
-- https://jamanetwork.com/journals/jamaneurology/fullarticle/791917

Plasma Exchange for Peripheral Neuropathy
-- https://nyulangone.org/conditions/peripheral-neuropathy-in-adults/treatments/plasma-exchange-for-peripheral-neuropathy