There is also new trial research, shared on a bulletin from my Cancer Center in Seattle, that when Breast cancer metastasizes to the bones, there hasn't been a reliable way to tell whether treatments people are on are working, when mainly in the bones. Patients may continue with ineffective treatments longer than necessary. There is a trial that followed 138 patients over 3-5 years that has shown that with FDG-PET/CT imaging (using sugar as a contrast), docs can predict progression-free survival after just 12 weeks. The scan shows how active cancer cells are, not just showing their shape or size.....whether the treatment is working, is an effective one. Sounds like a good development.