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Vitamin K: High Doses of MK-4 and MK-7 Show Promising Results
Osteoporosis & Bone Health | Last Active: Jun 6 10:56pm | Replies (107)Comment receiving replies
@osteoprob48 That doesn't mean you shouldn't consider taking MK-4 and MK-7, as there is no harm in taking the high doses. Sadly, nutrition and vitamins as treatments are not studied as much in the U.S. as they are in other countries.
I have fibromyalgia and was helped tremendously by LDN low-dose naltrexone which is not FDA-approved for fibromyalgia. However, it is used off-label and prescribed for this condition despite the lack of official approval. Studies have shown it helps many people with fibromyalgia and other inflammatory diseases.
There are even some studies that indicate LDN could help with osteoporosis. This article says: "Our results suggest that naltrexone increases bone mass due to osteoblast number increments caused by the OGFR signaling block. Opioid receptor blockers have potential as therapeutic agents for osteoporosis as well as opioid antagonists."
https://www.sciencedirect.com/science/article/abs/pii/S0024320519302395
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@osteoprob48 I also see it as @daisy17 describes above. MK4 and MK7 are supplements. There will never be great RCT research trials on Vit K because there is nothing that can be patented to get back the money from big expensive research.
Here is a good research overview from 2022:
https://pubmed.ncbi.nlm.nih.gov/35711002/
EXCERPT: "Conclusion: This meta-analysis and systematic review seemed to support the hypothesis that vitamin K2 plays an important role in the maintenance and improvement of BMD, and it decreases uc-OC and increases OC significantly at a long-term follow-up. Vitamin K2 supplementation is beneficial and safe in the treatment of osteoporosis for postmenopausal women."