Hello @bruce2666, welcome to Mayo Clinic Connect. Thank you for posting what helps with your neuropathy. I also have idiopathic small fiber PN but I don't have any pain with mine. I only have the numbness so there is nothing they can give you to help with numbness. They suspect my PN may be hereditary but they don't know and at this point for me it doesn't matter. Exercise helps me also and mostly keeps me focusing on something else other than my feet and numbness. I did look into laser treatments earlier but with no guarantees I decided it wasn't worth the cost for me.

If you don't mind my asking, you mentioned you have improved 50% after the laser treatments, how did were they able to measure the improvement? I take over the counter supplements to help with my PN and saw some improvement initially but then haven't seen much since. On the flip side, my PN hasn't seemed to gotten any worse the past 2 years so I count that as a big plus since my neurologist told me it would continue to get worse.

John