My husband, diagnosed with pancreatic cancer November 1, 2025 and hopefully having a Whipple in the next month, has been on Creon since that time. It has allowed him to eat and digest food MUCH better. He takes one capsule at the beginning of a meal and one in the middle of the meal. His tumor is in the head of his pancreas and his billiary duct was clogged so he has a stent in place.