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Hi All - I haven't posted in a while, so wanted to share my progress after 1 year on HRT. Some background; I just turned 63 and had a T12 Spine fracture in December, 2024. I was lucky to find a PA at my clinic who was open to prescribing HRT. I'm sharing a lot of data below and hope this helpful to others. I'm am VERY encouraged by the increase in BMD per the REMS scan and really hope this is accurate. I'll have my next DEXA this fall on the same machine and add the TBS score.
One interesting point is the difference in my last DEXA (osteoporosis in Spine/Osteopenia HIP) and REMS showed the opposite. Also, my first CTX/P1NP might have been falsely high due to 5 months post fracture. My 2nd P1NP is lower than I had hoped but my research using AI indicates the drop is normal on HRT.
I wasn't able to paste the excel data here and keep the formatting, so attached a pdf copy. Hope it works!
Replies to "Hi All - I haven't posted in a while, so wanted to share my progress after..."
@kshea2, thank you very much for sharing your experience. I am very sorry to hear about your fracture, and hope that you’ve recovered well.
The preliminary positive REMS results are very encouraging! Like yours, my bone markers (both CTX and P1NP) have decreased, though perhaps more in magnitude (i'm finishing up my second year of HRT currently). This is exactly what is expected for estrogen, as it acts mainly as an antiresorptive.
Wishing your upcoming DXA a similarly positive outcome later this year and continued steady progress.
@kshea2 These numbers are very encouraging and validating of my own experience on BHRT started at age 67. I also gained close to 5% after one year. I am due now for another REMS scan so will see if I've had any further gains after two years on BHRT. Thanks so much for sharing your numbers.
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Also on HRT, my P1NP went lower as well and my understanding is that as bone loss stabilizes the bone building process also slows. Similar to how these numbers would respond to a biophosphate med.
Congrats on numbers moving in positive direction. 😊