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Treatment of lung adenocarcinoma
Lung Cancer | Last Active: 12 hours ago | Replies (26)Comment receiving replies
@tongxiaozhi, I started taking Tagrisso after my lung cancer metastasized to my brain. My doctors surgically removed the cyst, and then I had four rounds of targeted radiation. A month after the radiation, I started taking Tagrisso alone in December 2020.
I did not have chemotherapy because chemotherapy does not cross the blood-brain barrier. However, since then, the Flaura 2 Phase III study has shown that the combination of Tagrisso and chemotherapy improves both progression-free survival (PFS) and overall survival (OS) compared to Tagrisso alone, https://www.ilcn.org/final-flaura2-os-data-show-osimertinib-plus-chemo-offers-benefit-compared-with-monotherapy/. But your oncologist will take into account your mother's age and overall health before prescribing chemotherapy. These decisions are never as simple as they look.
Your mother is lucky to have a child that is doing all this research on her behalf. I wish both of you all the best.
Matthew
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@flusshund “Thank you very much for your information. We consulted an oncologist, and she said that we could either take Osimertinib together with chemotherapy or start with Osimertinib alone. My mother plans to try Osimertinib alone for two months first, as she does not want to be too aggressive all at once. As you said, making these decisions is really not easy