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Treatment of lung adenocarcinoma

Lung Cancer | Last Active: 12 hours ago | Replies (26)

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Profile picture for tongxiaozhi @tongxiaozhi

My mother has stage IV lung adenocarcinoma. She currently has no obvious symptoms. She has an EGFR exon 21 mutation. Some doctors recommend osimertinib alone, while others suggest osimertinib combined with chemotherapy. We are feeling very conflicted about how to choose. I would really appreciate any advice. Thank you very much.

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Replies to "My mother has stage IV lung adenocarcinoma. She currently has no obvious symptoms. She has an..."

@tongxiaozhi there is research showing that patients like your mom that do both chemotherapy and osimertinib have a better/longer response. that said, chemotherapy has more difficult side effects. it's a case where you have to balance quality/quantity of life and consider your mom's overall health and priorities.
https://www.nejm.org/doi/full/10.1056/NEJMoa2306434