Darn, @zephyr2309. I imagine you have been hopeful ezetimibe would work. What a great thing Praluent is helping you!

I am not medically trained but I do have a life long experience trying anything and everything to treat my high cholesterol. Zetia was one that I said, ‘never again’! After 30+ years of trying my numbers are finally controlled and guess what - - - I am taking Zetia.

I can tell you what worked for me. I take it at night. I started with 1/2 pill every 4 days. I gradually increased it and settled in taking ezetimibe, 1/2 pill every night. The interesting thing is the effectiveness is not that much less than it would be taking a whole pill.

You may find Mayo Clinic’s Cardiovascular Continuing Medical Education (CME) podcast explaining updated approach valuable. It’ll take about 11 minutes:
- Mayo Clinic Cardiovascular CME: Statin Myopathy
Topics Discussed:
* Is any statin more or less likely to cause statin associated muscle symptoms?
* Are there any protective medications that can minimize statin myalgias?
* What newer non-statin agents have been shown to reduce risk of myalgias?
* How is treating high cholesterol levels becoming more like treating blood pressure?
https://cardiovascularcmemayoclinic.podbean.com/e/statin-myopathy/
I would love to hear your thoughts after listening. Please come back and let me know.

What is your LDL on Praluent? How long have you been taking it?