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PADCEV + KEYTRUDA: results and side effects
Bladder Cancer | Last Active: Jun 17 4:50pm | Replies (21)Comment receiving replies
@sperio I agree😊 I had a complete response on both drugs after 4 cycles last October and cancer is still non detectable based on scans last week and Signatera 2 weeks ago. That said I was having a VERY rough time and my medical oncologist thought it best to change direction a bit after 6 full cycles. (2 month hiatus from both drugs and now Keytruda only. ) The treatments that have become available to us are amazing, but generally not without issues. A wise patient advocate/ mentor I met in NY reminds us that it is different for everyone.😊
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@141emp Hi, I've got UTUC in kidney pelvis with planned kidney/ureter/bladder cuff removal surgery and was placed on Keytruda + Padcev to prep for surgery because ineligible for platinum chemotherapies due to decreased kidney function. Completed two cycles before the skin issues require decreased dose and eventually probably cease but Docs are very encouraged that Signatera went to zero after only one infusion. Telling me that for some patients the worst skin issues have the best long term outcomes. Now am weening off of steroids before surgery. So very grateful for the good care at our teaching hospital here in mid-atlantic.