@dadcue As for rare, I have nothing less than a dozen rare medical conditions, including being allergic to all NSAIDs as well as being allergic to Tylenol. If I ever become allergic to wine it's all over.

What I realize is biologics are not as simple to calculate half lives, and any calculated value based on research is only an estimate, not a fact I would bet on. Half lives of antibiotics are easier to understand and calculate. Not sure what the difference is and really don't care. Looking for medical-life balance in my golden years and it's elusive. I did not retire to have medical problems consume my work hours.