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Any experiences with Kevzara (sarilumab)?
Polymyalgia Rheumatica (PMR) | Last Active: May 1 3:40pm | Replies (114)Comment receiving replies
@tweetypie13 Kevzara has a half life of 10-14 days. That means that only half of a drug is in your system at the end of every half life. Doctors consider 5 half lives to be "completely out of your system" mark. Meaning 50-70 days for Kevzara. You are in this window.
Your CRP being up can be expected to continue going up without drug therapy intervention. I suspect this is why your doctor wants to start you back on Kevzara now and not later.
Ask your doctor about taking injection every 2 or 3 weeks rather than every week and getting 150mg rather than 200mg dose injectable.
Take care and know your doctor is there to keep you out of the ditch and not just help you get out of the ditch.
Replies to "@tweetypie13 Kevzara has a half life of 10-14 days. That means that only half of a..."
@jabrown0407
I’m going to be in the same position in this next year.
Since there isn’t much track record on this drug no one really knows if we can be drug-free at some point. That is the goal for all of us but we are in limbo with no real life long term experience of drug effectiveness. We are the guinea pigs or canary in the mine.
At least we can be hopeful for a better future than our ancestors.
@jabrown0407 Very helpful! Thank you!!
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@jabrown0407 Thx for your input. Truly appreciate it.
I’m a bit confused, easily….soo…
I was on a 200mg shot every 3 weeks for 4 months, when we stopped Kevzara.
No side symptoms etc. Last shot was 2/22/2026.
Would you mind reevaluating with this info in a more simplified way.
(I’m easily confused with half-life etc.)
Th K you