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Treatment options and cribriform
Prostate Cancer | Last Active: May 4 6:27am | Replies (15)Comment receiving replies
@mozir
All I can do is give you the Technical information about the chance of reoccurrence with large cribriform.
Large cribriform pattern in prostate cancer is a significant adverse feature, highly associated with increased risks of biochemical recurrence (BCR) after prostatectomy. Studies indicate large cribriform patterns correlate with higher Decipher scores, 16-fold higher risk of BCR, and, in cases of severe cribriform, recurrence rates can be as high as 75%.
This could be because some of the cancer gets out of the prostate before it gets recognized. Like dormant cells that get sent to many different places in your body, and hide out so they can’t even be seen, but if you get stressed, they can pop up and become cancerous again.
Prostate cancer has weird ways to propagate.
Replies to "@mozir All I can do is give you the Technical information about the chance of reoccurrence..."
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@jeffmarc wrote:
"Large cribriform pattern in prostate cancer is a significant adverse feature, highly associated with increased risks of biochemical recurrence (BCR) after prostatectomy. Studies indicate large cribriform patterns correlate with higher Decipher scores, 16-fold higher risk of BCR, and, in cases of severe cribriform, recurrence rates can be as high as 75%."
Can you share a citation for this? Those hazard ratios are much higher than I've seen in the publications I've personally reviewed, and would love to review those add'l sources once you share.