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← Return to Rituximab or Remicade for Rheumatoid Arthritis RA
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Rituximab or Remicade for Rheumatoid Arthritis RA
Autoimmune Diseases | Last Active: 23 hours ago | Replies (28)Comment receiving replies
I am also watching CAR-T therapies for systemic sclerosis. So far, some positive results have been reported in Phase I/II studies. However, toxicities like cytokine release syndrome CRS and ICANS (neurological deficits like aphasia) are a concern. Current clinical trials in autoimmune diseases report that all toxicities were reversable. However, CAR-Ts in oncology report more serious and long-lasting neurological deficits that may persist for months.
Something to think about.
With these known side effects, I already had three doctors recommending CAR-T as the best choice. I am still thinking and waiting for more data. Best wishes
Replies to "@judyresnick I am also watching CAR-T therapies for systemic sclerosis. So far, some positive results have..."
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@altabiznet
I haven’t looked at the cancer studies but I was told that they can affect the neurological issues. Like Parkinson’s. Horrible disease. That’s why we wait and watch. She just got out ICU for sepsis and toxic shock. Thats from
Trying the new immunosuppressants. She keeps getting infection from them and remains in long term use of steroids. Destroyed her teeth, her bones are bad and she gets terrible tears from long erm steroid use smothered is no win yet. Maybe a higher price car t will it seems like refine the neurological effects.
I am very hopeful about this therapy. It’s the first thing that anyone ever said put them in remission. Nothing does it so I wish you good luck in my daughter. Good luck in fact all of you need some luck.